MD/PhD Program “Molecular Medicine“ Hannover Medical School

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MD/PhD Program “Molecular Medicine“ Hannover Medical School Report 2005 MD/PhD Program “Molecular Medicine“ Hannover Medical School (MHH) Responsible…
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MD/PhD Program “Molecular Medicine“ Hannover Medical School Report 2005 MD/PhD Program “Molecular Medicine“ Hannover Medical School (MHH) Responsible Univ. Prof. Dr. Reinhold E. Schmidt Chairman MD/PhD Program Carl-Neuberg Str. 1 30625 Hannover Tel: 0511-532-6656 immunologie@mh-hannover.de MD/PhD committee: Prof. Dr. A. Gossler, Prof. Dr. G. Brabant, Prof. Dr. C. Baum, Prof. Dr. C. Klein, Prof. Dr. R. Lichtinghagen, Prof. Dr. M. Gaestel, HD Dr. B. Sodeik, PD Dr. T. Tschernig, Dr. E. Jäckel, Dr. C. Nassenstein (final exam Nov. ‘05), Dr. E. Hesse/ Prof. Dr. D. Gadzicki, Dr. M. Ünalan, M. Rhein Dr. Susanne Kruse, Marlies Daniel MD/PhD Office OE 9117 Carl-Neuberg Str. 1 30625 Hannover Tel. 0511-532-6011 Kruse.susanne@mh-hannover.de Daniel.marlies@mh-hannover.de Internet: www.mh-hannover.de/studium/phd Chairman of the MD/PhD program The MD/PhD program “Molecular Medicine“ was established in autumn 2000. Our program has meanwhile become one of the leading PhD programs in Germany due to excellent interdisciplinary cooperation between the Hannover Medical School (MHH), the University, the School of Veterinary Medicine Hannover and the Gesellschaft für Biotechnologische Forschung (GBF), Braunschweig, due to the support of the International Promotion Program (IPP) by DAAD and DFG. We are also proud to have international outstanding teachers, such as Prof. Fritz Melchers, in our program. It is also the first German PhD program which has been accreditated according to European standards (modules ECTS). There is a good ratio between medical students and students from life sciences as well as between German and foreign students. This program attracts great national and international interest. Additionally, the MD/PhD program is the basis for the Hannover Biomedical Research School (HBRS) founded in 2003, which is extremely successful in integrating all postgraduate programs at MHH. Joint curricula have been established. Currently, HBRS is applying for funds in the Excellence Initiative and has already passed the first round. We meanwhile can be proud of three classes which have successfully graduated from the program. They are ambassadors for MHH around the world. Many sponsors are generously providing support for our workshop or even better stipends for our students. Many thanks to everyone who has supported this MD/PhD program, especially to those students who determine the excellence of the program. Reinhold E. Schmidt, MD Professor of Medicine and Immunology Dean of Hannover Biomedical Research School We express our thanks to our sponsors: “Friends of MHH” Martin Lawrenz, Hannover Table of Contents I. Current Status, Problems and Prospects _________________________ 7 1. Current Status ____________________________________________________________________ 7 2. Common Rules ___________________________________________________________________ 10 3. Cooperation with International Institutes _____________________________________________ 11 4. Success and measures for implementation ____________________________________________ 12 II. Measures and Results _______________________________________ 13 1. Personnel _______________________________________________________________________ 13 1.1. Scientific collaborators and administrative personnel__________________________________________ 13 1.2. Tutors ______________________________________________________________________________ 14 2. Language courses_________________________________________________________________ 14 3. Social Activities __________________________________________________________________ 14 4. Organization of Educational Material ________________________________________________ 15 5. Marketing Measures ______________________________________________________________ 15 6. Guest Lectures and additional colloquia ______________________________________________ 16 7. Travel __________________________________________________________________________ 17 8. Visits abroad by the graduate students _______________________________________________ 17 6 I. Current Status, Problems and Prospects 1. Current Status Statistics Applications 2005 Country Number of applicants Now in the program Total female male total female male Germany 25 14 11 8 4 4 Western Europe: 12 5 7 - - - Central and Eastern 32 17 15 - - - Europe North America: 2 1 1 - - - Latin America: 4 3 1 1 - 1 Africa, Subsahara: 28 10 18 1 1 North Africa and Middle 18 5 13 East: Asia, Australia and 263 84 179 10 4 6 Oceania: Total: 384 139 245 20 9 11 Final exams in the MD/PhD program 2005: 12 students did their final exams in November 2005. From 18 students of the year 2002, 9 did their final exams after exactly 3 years = 50%, seven plan to finish after 3,5 years, two after 4 years. Detailed Description At the moment (February 2006) there are 70 students in the program [30 women and 40 men; 51 international and 19 Germans; 19 medical students (incl. veterinary students) and 51 life scientists]. The international students come from Bolivia (1), China (5), Columbia (1), Estonia (1), Ethiopia (1), Georgia (1), Hungary (1), India (30), Indonesia (1), Kenia (2), Mongolia (1), Poland (1), Slovakia (1), Syria (1), the Netherlands (1), Ukraine (1) and Zimbabwe (1). 7 The students are either financed by the corresponding departments or by scholarships (DAAD; industry etc.). We are very grateful that in 2005 the MHH provided for the second time ten half stipends (about 1.000,-Euro/month for 18 months) for the best ten students of the ranking list after selection. Concerning selection of the new students, a 3-step level procedure was introduced in 2002. It consists of: 1. preselection by the PhD commission, 2. a written test in the individual home countries, 3. an interview (in 2005 in Hannover, New Delhi and Hyderabad, India). In 2002 an extensive application form was developed, which as further improved in 2005. Now, there is a joint application form together with the PhD program “Infection Biology”. The selection of the applicants is based on qualification only. The accepted candidates are supposed to choose a department and a research project themselves. This means that there can be bottle-necks regarding the guarantee of the financing of the students. For this reason scholarships were applied for with e.g. the Excellence Initiative of the German government. Students work on a 3-year research project in one of the departments of the MHH or at cooperating institutes (see list of students). In addition, there is an obligatory program of teaching consisting of seminars and tutorials (see list of lecturers). In October 2003, the Graduate School: “Hannover Biomedical Research School” (HBRS) was founded at MHH (director: Prof. Dr. R.E. Schmidt, office: Dr. S. Kruse). Here, all graduate programns [PhD (MD/PhD “Molecular Medicine” and PhD “Infection Biology”, Graduate Colleges (GRK 705, European GRKs “Pseudomonas” and “Strategiesof human pathogens to establish acute and chronic infection”), etc.] are coordinated. In 2004, a joint Curriculum of the HBRS [MD/PhD program, PhD program “Infection Biology” (speaker: Prof. Dr. Förster) and Miditrain (GBF, EST Marie Curie, speaker: Prof. Dr. Hauser)] was established in order to bundle resources. In the first year, basics and methods of biology and medicine are taught. There are special in-depth seminars for medical students as well as life scientists. Furthermore, specific tutorial series for the MD/PhD program respective PhD “Infection Biology”/Miditrain were organized. During the second academic year, focus lies more on current research projects (applied aspects). Since 2003, four main foci have been established in the MD/PhD program: Immunology; Infection; Oncology and Differentiation; Genetics and Cell Biology (Fig. 2). Besides an extensive English curriculum, guest seminars, scientific colloquia, discussions with the supervisors and technical practical courses took place. 8 Most important are the so-called “soft skills“ as well as seminars about “Research Ethics” (members of the institute of “Science and Ethics”, Bonn), “Ethics“ (Prof. Schmidtke), “Animal Experiments“ (Prof. Hedrich), “Scientific Writing“ (Dr. Kruse), “Presentation techniques” (Prof. Dierks), “Bioinformatics” (Zheng, GBF), “Intercultural communication” (together with Göttingen and Ulm) etc. The students keep book about all seminars. At the end of every semester an evaluation of the educational programs and lecturers is performed. After 18 months, students give an oral intermediate exam in the respective main subject and the subject of the co-supervisor (presentation and discussion of a research paper). After 3 years the final exam takes place in form of a public disputation. In 2005, twelve MD/PhD students (Syed Raza Ali, India, Clinical Immunology; Srinivas Annavarapu Rao, India, Endocrinology; Wahid Ansari, India, Clinical Imunology; Meta Djojosubroto, Indonesia, Gastroenterology; Thomas Gebhardt, Germany, Gastroenterology; Claudia Karacsonyi, Argentina, Cell Biology; Varsha Kumar, India, Clinical Immunology; Jianyun Liu, Visceral Surgery; Christina Nassenstein, Germany, Fraunhofer Institute; Axel Schambach, Germany, Hematology and Oncology; Amar Deep Sharma, India, Gastroenterology; Frank Traub, Germany, Pathology) sucessfully finished the program, whereby 9 from altogether 18 of the year 2002 needed exactly 3 years. The remaining six students will perform the final exams either on June 9th, 2006 (seven) or November 10th, 2006 (two). The ECTS System was introduced (credit points = cp; see Fig. 1). The program was accreditated according to European standards by ZEvA on December 9th, 2003. Figure 1. Study Structure MD/PhD Program “Molecular Medicine“ Year 1 Year 2 Year 3 3-year PhD project work (125 cp) PHD Annual presentation in department (3x; 10 cp) thesis Journal club (3x; 3 cp) Public annual presentation/project report (3x; 10 cp) and Talk/presentation on international congress (2 cp) Final Basics (seminar Complex and clinical exam and tutorial; 3 h per systems (seminar and week; 8 cp) tutorial; 3 h per week; 8 cp) Project-orientated seminars/courses (80 h; 8 cp) Interdisciplinary seminars/courses (60 h; 6 cp) Intermediate Exam after 18 months 9 Figure 2. Curriculum 2005/6 In September 2002, a German-wide network of biomedically orientated PhD programs was established (currently 15 members). Further improvement of the coordination of selection procedures (exams and interviews) was achieved. In 2005, the second joint workshop on “Intercultural communication” took place in Bergkirchen, organized by the PhD programs of Ulm, Göttingen and Hannover. 2. Common Rules On 15.12.99, a rule for the MD/PhD program was passed by the senate of Hannover Medical School. This rule unites a regulations for studies and exams. On 12.02.02, the MD/PhD program received authorization from the Lower Saxony Ministry for Science and Culture to alternatively award besides the PhD title for scientists the title Dr. rer. nat. Such changes in the rules and adaption to the program situation were passed by the senate on 04.06.02. On 11.02.04, the rules were adapted to the suggestions by the committee of referees for accreditation and were overall updated, same accounts for April 2005. The PhD rules consider all aims of the program. 10 3. Cooperation with International Institutes Fortunately, within the MHH there is an active exchange, i.e. participation of almost all scientifically active departments in the MD/PhD program – whether by means of active organizing within the MD/PhD commission, by supervising the MD/PhD students at the research laboratories or as lecturers in the numerous educational programs. This goes for the basic scientific as well as for the clinically orientated departments, for example: Biochemistry, Cardiology, Cell Biology, Clinical Immunology, Dermatology, Gastroenterology-Hepatology-Endocrinology, Genetics, Hematology, Heart and Thoracic Surgery, Immunology, Microbiology, Molecular Biology, Nephrology, Oncology, Pathology, Physiology, Rheumatology, Tumor Biology, Virology, Visceral and Transplantation Surgery, etc. Therefore intensive cooperation exists between collaborators (Post-docs etc.) from Graduate Colleges with the MD/PhD program. Moreover, the “Graduate School” (HBRS) was founded in October 2003. There is close cooperation between the graduate and PhD programs of the School of Veterinary Medicine Hannover, also concerning lecturers and students. In addition, there are very close cooperations to the GBF in Braunschweig and the Fraunhofer Institute (ITEM) in Hannover. Thanks to the scientists of the MHH there is already intensive cooperation with European and internationally very well-known research institutes (e.g. also by means of the European Graduate College “Pseudomonas: Pathogenicity and Biotechnology“). Of course, the PhD students profit from this cooperation, too. A constant exchange and participation in education and research exists with the following institutes: a) national: ã German Research Center for Biotechnology (GBF); Braunschweig ã School of Veterinary Medicine, Hannover ã Fraunhofer Institute for “Toxicology and Experimental Medicine” (ITEM), Hannover ã Max Planck Institute for “Experimental Endocrinology“, Hannover ã Institute for “Animal Breeding”, Mariensee (FAL) ã Center for Stem Cell Research, Gatersleben There is intensive cooperation with these national institutes as well as concerning education (lecturers) and concerning research, i.e. making three year projects available or the function of scientists as co- supervisors. b) international (especially with): ã Centre for DNA Fingerprinting (CDFD), Hyderabad, India With Prof. Dr. S. Hasnain there has been intensive contact since 2002 (see guest lecturer and trip to India). The establishment of a mutual “summer school“ is planned and the exchange of scientists. 11 c.) Economy/Industry (especially with): Solvay GmbH Hannover, Schering AG Berlin and Novartis GmbH Basel Industry excursions (e.g. Solvay AG, Hannover; Bayer AG, Research Center, Wuppertal) are regularly taking place. 4. Success and measures for implementation In 2005, twelve students successfully finished the MD/PhD program (see above). Some of the finalists continue to work at MHH or German universities (medical consultant, Postdoc etc.). Eight of them already went to work as Postdocs abroad (UK, USA, Australia, China, Switzerland). The MD/PhD program plans to establish an ALUMNI organization on the long-term range. At the moment the PhD students form a sub-group of the MHH Alumni e.V. The MHH has guaranteed to continue financial support of the MD/PhD program after discontinuation of the support by the DAAD/DFG (after 5 years). The DAAD has extended their financial support for 2005 and 2006 after an extremely successful evaluation of the program. The MHH already provided ten grants to excellent stdents per year (see above). The MD/PhD program plays a key role (scientific, organization) in Hannover Biomedical Research School (HBRS). The establishment of the Graduate School will be considered in the future budget (personel and consumables). Currently, MHH is applying for funds for HBRS in course of the Excellence Initiative. Furthermore, the accreditation (see above) implements the program. The program was very successful in gaining sponsors, either for the annual workshop, the year book or for student’s grants (see list on page 6). A sponsoring concept as well as special flyers were developed. 12 II. Measures and Results The MD/PhD Program “Molecular Medicine“ started in winter semester 2000/01. Since 01.01.2002, the program is supported by the DAAD/DFG by means of the “International Promotion Program” (IPP). 1. Personnel Within the IPP the posts for a scientific coordinator (full time) and funds for assistant students (see “non scientific care”; 10 hours/week) have been granted. 1.1. Scientific collaborators and administrative personnel Since 01.05.2002, Dr. Susanne Kruse has been working on the program as scientific coordinator. She is a graduated biologist and, therefore, most competent for the sector “Molecular Medicine”. She has various tasks; she is responsible for the total coordination and organization of the MD/PhD program and HBRS, e.g. ã Consultation of the PhD students and applicants ã Organization and coordination of the application and selection procedure ã Cooperation with the PhD commission and HBRS ã Processing of the PhD commission meetings ã Contact to supervisors and lecturers of the Medical School and cooperating institutes ã Public relations (articles, homepage design etc.) ã Marketing (flyers, poster, advertisements etc.) ã Fund raising (incl. sponsors); applications (DFG, BMBF etc.) ã Planing and coordination of the curriculum (including “Soft skills”) ã Organization of workshops/seminars ã Presentation of the seminar “Scientific Writing“ ã Evaluation of seminars and tutorials ã Preparation of exams and coordination ã Organization of the inauguration, non scientific care and social activities ã Contact to DAAD and other PhD programs (esp. MD/PhD Network) ã Administration of the budget ã Instruction of the person in charge (Mrs. Daniel), the German teacher (Mrs. Marotz) and assistant students (see below!) 13 Mrs. Marlies Daniel works at the PhD Office (full time) as person in charge/correspondant. Her position is financed by the Hannover Medical School. Mrs. Daniel supports Dr. Kruse with the coordination und organization of the MD/PhD program. She is responsible for the total correspondence, telephone calls, organization of the application procedure, taking care of the students (esp. during the training period: organization of accommodation, banks, insurance etc.), statistics etc. 1.2. Tutors In 2005, Tracey Gillman, E. Makono Mayhar (Mike), Ruth Knorr und Florian Bittner have been employed as assistant students on an hourly basis. These tutors especially take care of the MD/PhD students in close cooperation with the “International Office” (concerning culture, geography, history and institutions), help at German authorities, help at International evenings and with the homepage. 2. Language courses Mrs. Petra Marotz has been employed as the German teacher since 01.10.2002 (hourly basis) with a lectureship. She teaches the foreign PhD students in two courses à 2 hours/week. This concerns a course for beginners and an advanced course (1 year experience). A total of over 20 PhD students of HBRS participate in the courses. 3. Social Activities ã On 19.02.05, a joint “Bowling“ evening for students of all PhD programs was organized. ã On 30.04.05, a day excursion by bus to Bremen was taking place (Science Center) in close cooperation with the International Office. ã Regular tables were held in the Maza, City Centre. ã On 07.07.05, summer term was closed with an international barbeque for all PhD students, lecturers and supervisors in HBRS. ã On 08.07.05, an excursion to the Biotech company „BioVision AG“ Hannover was organized with about 20 students from HBRS. 14 ã Orientation weeks (04.10.-17.10.05) were financially supported by the “WIN“ program (Welcome in Niedersachsen) of Lower Saxony. ã The opening of term / welcome of new students was celebrated on 17.10.05. All students, supervisors and lecturers of the MD/PhD program “Molecular Medicine“ and PhD program “Infection Biology” as well as the president of MHH and several guests (e.g. State secretary Dr. Lange, MWK) participated. Invited spealer was Prof.’in Dr. U. Beisiegel (University Clinics Hamburg Eppendorf, see also 6.), musical introduction by: A. Barkhoff + Band. ã On 11.11.05, the festive ceremony after the final exams took place. Invited guest speaker was Prof. Dr. Braun (Max-Planck Institute, Bad Nauheim) (see also under 6.), musical introduction by Nora Teschner (Cellotrio). ã On 25.11.05, students visited a variete in cooperation with the International Office. ã On 14.12.05, an international Christmas Party
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